This paper divides technological innovation into two stages: technology development and technology transfer. Then the authors use the panel data of 28 manufacturing industries during 2003–2012 to test the econometric regression model for the industry of the sub stages, which is a regulation on technological innovation in the environment. The results show that: (1) environmental regulation has a significant role in promoting China’s manufacturing technology research patent achievements, and technology into new products, and this indicated that “Porter hypothesis” in the manufacturing sector has been verified; (2) R&D and transfer expenditure have a positive impact on technological innovation. Finally, the authors put forward the corresponding policy recommendations for industry of the environmental regulation on the impact of technological innovation in phases.