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篇目详细内容 |
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【篇名】 |
The molecular epidemiological study of colistin-only-sensitive strains in multi-drug resistant Acinetobacter baumannii |
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【刊名】 |
Frontiers of Medicine in China |
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【刊名缩写】 |
Front. Med. China |
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【ISSN】 |
1673-7342 |
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【EISSN】 |
1673-7458 |
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【DOI】 |
10.1007/s11684-007-0083-6 |
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【出版社】 |
Higher Education Press and Springer-Verlag |
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【出版年】 |
2007 |
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【卷期】 |
1
卷4期 |
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【页码】 |
423-428
页,共
6
页 |
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【作者】 |
YANG Li;
HAN Lizhong;
SUN Jingyong;
YU Yunsong;
NI Yuxing;
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【关键词】 |
colistin; Acinetobacter baumannii; epidemiological study; cross-infection |
【摘要】 |
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This paper reported the epidemiology of the colistin-only-sensitive Acinetobacter baumannii(COS-AB) in a tertiary teaching hospital in China. We analyzed the clinical data of 136 COS-AB isolates from June 2004 to May 2005 and collected 66 A.baumannii isolates in which 33 strains were COS-AB, and the rest were non-COS-AB. Random amplified polymorphic DNA (RAPD) analysis (primer ERIC2 and 272) showed that all COS-AB were identical, while pulsed-field gel electrophotesis (PFGE) analysis showed two separate genotypes of these COS-AB which were distinctly different from that of non-COS-AB. The COS-AB from burn wards showed the identical PFGE pattern which was distinguished from the genotype of COS-AB in other departments, mainly surgical systems. The cross-infection was severe and strict methods of disinfection and sterilization should be implemented. Meanwhile, the epidemiology of COS-AB in environment and patients should be closely monitored. The PFGE analysis is a reliable method of A.baumannii typing. |
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