|
|
|
篇目详细内容 |
|
【篇名】 |
A 7-year follow-up study of the features and transformations of elderly male patients with OGTT-1h hyperglycemia |
|
【刊名】 |
Frontiers of Medicine in China |
|
【刊名缩写】 |
Front. Med. China |
|
【ISSN】 |
1673-7342 |
|
【EISSN】 |
1673-7458 |
|
【DOI】 |
10.1007/s11684-008-0076-0 |
|
【出版社】 |
Higher Education Press and Springer-Verlag |
|
【出版年】 |
2008 |
|
【卷期】 |
2
卷4期 |
|
【页码】 |
396-399
页,共
4
页 |
|
【作者】 |
TIAN Hui;
PAN Changyu;
LU Juming;
LI Chunlin;
ZHONG Wenwen;
CAO Xiutang;
|
|
【关键词】 |
glucose tolerance test; clinical features; transformation |
【摘要】 |
|
The aim of this paper is to investigate the clinical features and transformation of elderly male patients with normal blood glucose levels at fasting and 2 hours after glucose intake but with hyperglycemia (≥ 11.1 mmol/L) 1 hour after oral glucose tolerance test (OGTT-1h HG). Seven years of follow-up visits were performed on 189 elderly male outpatients with OGTT-1h HG and data was recorded on their body mass index (BMI), blood pressure, serum cholesterol and triglyceride test results and on their glucose tolerance changes every 1–2 years after taking OGTT; their possible causes were analysed. Follow-up visits revealed that 19 patients with OGTT-1h HG were diagnosed with diabetes (10.1%), 78 patients with impaired glucose tolerance (IGT, 41.3%), 2 patients transformed to normal glucose tolerance (NGT, 1.1%) and the remaining 90 patients (47.6%) remained unchanged. Synchronized comparison with IGT patients showed that the ratio of OGTT-1h HG patients turning to diabetes was lower than that of IGT patients (21.1%, χ2 = 13.05, P < 0.01), and the ratio of OGTT-1h HG patients transforming to NGT was slightly higher (0.4%, χ2 = 2.46, P > 0.05). The prevalence of complications of hypertension, coronary heart disease, cerebral vascular diseases and dyslipidemia in patients with OGTT-1h HG were higher than those with NGT (P < 0.05) and were similar to that of IGT patients. As a special phenotype of OGTT and as part of an abnormal glucose tolerance conformation, patients with OGTT-1h HG warrant special attention, since about half of them were found to have developed diabetes or IGT, and their risk of suffering from vascular diseases were also increased. |
|
