|
|
|
篇目详细内容 |
|
【篇名】 |
Epigenetic reprogramming: roads to pluripotency |
|
【刊名】 |
Frontiers in Biology(Formerly known as Frontiers of Biology in China) |
|
【刊名缩写】 |
Front. Biol. |
|
【ISSN】 |
1674-7984 |
|
【EISSN】 |
1674-7992 |
|
【DOI】 |
10.1007/s11515-010-0003-z |
|
【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
|
【出版年】 |
2010 |
|
【卷期】 |
5
卷1期 |
|
【页码】 |
8-11
页,共
4
页 |
|
【作者】 |
Wei LI;
Qi ZHOU;
|
|
【关键词】 |
Epigenetic reprogramming; pluripotency; regenerative medicine |
【摘要】 |
|
Epigenetic reprogramming provides valuable resources for customized pluripotent stem cells generation, which are thought to be important bases of future regenerative medicine. Here we review the commonly used methods for epigenetic reprogramming: somatic cell nuclear transfer, cell fusion, cell extract treatment, inducing pluripotency by defined molecules, and briefly discuss their advantages and limitations. Finally we propose that mechanisms underlying epigenetic reprogramming and safety evaluation platform will be future research directions. |
|
