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篇目详细内容 |
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【篇名】 |
LC-ELSD analysis for simultaneous determination of five components in the Xue-Fu-Zhu-Yu capsules |
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【刊名】 |
Frontiers of Chemical Engineering in China |
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【刊名缩写】 |
Front. Chem. Eng. China |
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【ISSN】 |
1673-7369 |
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【EISSN】 |
1673-7474 |
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【DOI】 |
10.1007/s11705-009-0309-z |
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【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
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【出版年】 |
2010 |
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【卷期】 |
4
卷1期 |
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【页码】 |
96-101
页,共
6
页 |
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【作者】 |
Ying GAO;
Wenyuan GAO;
Fengge LI;
Xinying YANG;
Xuan DONG;
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【关键词】 |
column liquid chromatography; quantitative analysis; traditional Chinese medicine; Xue-Fu-Zhu-Yu capsule |
【摘要】 |
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A reliable and accurate liquid chromatography with evaporative light scattering detection (LC-ELSD) method was developed for simultaneous determination of five constituents in Xue-Fu-Zhu-Yu capsule, a widely used prescription of traditional Chinese medicine (TCM). The chromatographic separation was performed on a Symmetry C18 column (150mm×4.6mm, 5.0μm) using gradient elution of acetonitrile and water (containing 1.0% acetic acid). The flow rate was 0.6mL/min and the temperature of column was 30°C. A good linearity correlation was obtained over the investigated concentration ranges. Recoveries of the five components varied from 97.31% to 99.84% (RSD<4.0%). The validated method was successfully applied to the quality assessment of Xue-Fu-Zhu-Yu capsule. |
