|
篇目详细内容 |
|
【篇名】 |
Implications of astrocytes in neurovascular coupling |
|
【刊名】 |
Frontiers of Medicine in China |
|
【刊名缩写】 |
Front. Med. China |
|
【ISSN】 |
1673-7342 |
|
【EISSN】 |
1673-7458 |
|
【DOI】 |
10.1007/s11684-010-0019-4 |
|
【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
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【出版年】 |
2010 |
|
【卷期】 |
4
卷1期 |
|
【页码】 |
43-45
页,共
3
页 |
|
【作者】 |
You ZHOU MD;
Chang-Kai SUN MD;
|
|
【关键词】 |
cerebral blood flow; neurovascular coupling; astrocyte |
【摘要】 |
|
Normal brain function requires continuous supply of oxygen and glucose in a strict manner. The close spatial and temporal relationship between neural activity and cerebral blood flow (CBF) is termed as neurovascular coupling, which is dependent or not dependent on astrocytes. The increase in flow evoked by brain activity is mediated by the concerted action of multiple mediators that originate from different cells and act at different levels of the cerebral vasculature. More studies are needed for further understanding the precise mechanisms underlying neurovascular coupling, especially the implications of astrocytes. |
