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篇目详细内容 |
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【篇名】 |
Research advances of Legionella and Legionnaires’ disease |
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【刊名】 |
Frontiers of Medicine in China |
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【刊名缩写】 |
Front. Med. China |
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【ISSN】 |
1673-7342 |
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【EISSN】 |
1673-7458 |
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【DOI】 |
10.1007/s11684-010-0036-3 |
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【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
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【出版年】 |
2010 |
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【卷期】 |
4
卷2期 |
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【页码】 |
166-176
页,共
11
页 |
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【作者】 |
Xiao-Yong ZHAN MD;
Chao-Hui HU PhD;
Qing-Yi ZHU MD;
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【关键词】 |
Legionella; Legionella pneumophila; diagnosis; Legionnaires’ disease |
【摘要】 |
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Legionella is a causative agent of legionellosis or Legionnaires’ disease. Infection with Legionella spp. is an important cause of community and hospital-acquired pneumonia. Moreover, infection with Legionella is one of the most common causes of severe pneumonia in community settings, and Legionella is isolated in 40% of hospital-acquired pneumonia cases. The clinical features of legionellosis or Legionnaires’ disease are not unique, which makes the diagnosis challenging. Macrolides and fluoroquinolones are the most widely used drugs in treatment. Early recognition, treatment and effective measures for prevention and control of the disease are important and required. Although there have been a lot of methods for diagnosis of Legionella infection, they were often time-consuming or complex, not suitable for clinical purposes. This review summarizes available information regarding the microbiology, taxonomy, epidemiology, pathogenesis and diagnosis of Legionnaires’ disease, with an emphasis on the laboratory diagnosis of infection with Legionella spp. |
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