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篇目详细内容 |
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【篇名】 |
Oridonin: A promising anticancer drug from China |
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【刊名】 |
Frontiers in Biology |
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【刊名缩写】 |
Front. Biol.
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【ISSN】 |
1674-7984 |
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【EISSN】 |
1674-7992 |
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【DOI】 |
10.1007/s11515-010-0610-8 |
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【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
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【出版年】 |
2010 |
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【卷期】 |
5
卷6期 |
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【页码】 |
540-545
页,共
6
页 |
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【作者】 |
Wenjing ZHANG;
Qilai HUANG;
Zi-Chun HUA;
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【关键词】 |
oridonin; chemical structure; antitumor; signal transduction |
【摘要】 |
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Oridonin, a diterpenoid isolated from Rabdosia rubescens (Hemsl.) Hara, has been proved to possess remarkable anticancer activity, in addition to its potential in antiinflammation and antibacteria. The purpose of this article is to review current progress in oridonin concerned about a relationship between the chemical structure/modifications and its anticancer activity and to discuss the molecular mechanisms underlying its anticancer activity, such as suppression of tumor proliferation and induction of tumor cell death, and the cell signal transduction in anticancer activity of oridonin. |
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