|
|
|
篇目详细内容 |
|
【篇名】 |
Alcohol and tea consumption in relation to the risk of nasopharyngeal carcinoma in Guangdong, China |
|
【刊名】 |
Frontiers of Medicine in China |
|
【刊名缩写】 |
Front. Med. China |
|
【ISSN】 |
1673-7342 |
|
【EISSN】 |
1673-7458 |
|
【DOI】 |
10.1007/s11684-010-0280-6 |
|
【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
|
【出版年】 |
2010 |
|
【卷期】 |
4
卷4期 |
|
【页码】 |
448-456
页,共
9
页 |
|
【作者】 |
Hong-Lian RUAN;
Feng-Hua XU;
Wen-Sheng LIU;
Qi-Sheng FENG;
Li-Zhen CHEN;
Yi-Xin ZENG;
Wei-Hua JIA;
|
|
【关键词】 |
nasopharyngeal carcinoma; case-control study; alcohol consumption; tea consumption |
【摘要】 |
|
To investigate whether alcohol and tea consumption has an etiological association with nasopharyngeal carcinoma (NPC) in a high-incident population, a large scale case-control study was conducted. The study included 2846 individuals in Guangdong Province, China, with 1387 newly diagnosed cases of NPC and 1459 frequency-matched controls. Exposure histories of alcohol and tea consumption were obtained via personal interviews. Information regarding socio-demographic characteristics (age, sex, education, dialect and household type), family history of NPC, Epstein-Barr virus (EBV) infection, dietary habits and other potential confounding factors was also studied. An analysis was performed using unconditional logistic regression to calculate odds ratios (OR) and 95% confidence intervals (CI). The risk of NPC was found to be associated with habitual alcohol consumption and tea consumption. Tea consumption has been associated with a decreased occurrence of NPC (OR= 0.62), while consumption of alcohol was associated with a complex effect. Specifically, moderate consumption of alcohol was associated with decreased risk of NPC, while overuse, especially strong distillate spirits, appeared to be a risk factor. |
|
