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篇目详细内容 |
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【篇名】 |
Preparation of chitosan/alginate microcapsules by high-voltage electrostatic method |
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【刊名】 |
Frontiers of Chemistry in China |
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【刊名缩写】 |
Front. Chem. China |
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【ISSN】 |
1673-3495 |
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【EISSN】 |
1673-3614 |
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【DOI】 |
10.1007/s11458-011-0230-0 |
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【出版社】 |
Higher Education Press and Springer-Verlag Berlin
Heidelberg |
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【出版年】 |
2011 |
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【卷期】 |
6
卷1期 |
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【页码】 |
48-53
页,共
6
页 |
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【作者】 |
Yufei AI;
Shuang GUO;
Qi ZHANG;
Jing QIAO;
Xuanyue GAO;
Jun NIE;
Dongzhi YANG;
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【关键词】 |
chitosan; sodium alginate; electrospraying |
【摘要】 |
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Chitosan and sodium alginate have the opposite charges; they can become a gelatin by the electrostatic attraction, High-voltage electrostatic droplet generator method was used to prepare chitosan-sodium alginate microcapsule. Multi-layer chitosan-sodium alginate microcapsule was prepared through layer-by-layer self-assembly, and the morphology was investigated. In addition, the release property of ofloxacin in microcapsules was studied by UV-Vis microscopy under different conditions such as pH value, layer number, etc. The results showed that the prepared microcapsules have a smooth surface with average particle size about 100 μm. The result of controlled release indicated that the prepared microcapsules are pH-independent, and the rate of release decreased when the layer number increases. |
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