篇目详细内容 |
【篇名】 |
Shape-memory and biocompatibility properties of segmented polyurethanes based on poly(L-lactide) |
【刊名】 |
Frontiers of Chemistry in China |
【刊名缩写】 |
Front. Chem. China |
【ISSN】 |
1673-3495 |
【EISSN】 |
1673-3614 |
【DOI】 |
10.1007/s11458-007-0063-z |
【出版社】 |
Higher Education Press and Springer-Verlag |
【出版年】 |
2007 |
【卷期】 |
2
卷4期 |
【页码】 |
331-336
页,共
6
页 |
【作者】 |
PING Peng;
WANG Wenshou;
ZHANG Peibiao;
CHEN Xuesi;
JING Xiabin;
|
【关键词】 |
polyurethane; poly(L-lactide); shape memory; biocompatibility |
【摘要】 |
A series of segmented poly(L-lactide)-polyurethanes (PLA-PUs) were synthesized by a twostep method, with oligo-poly(L-lactide) (PLA) as the soft segments and the reaction product of 2,4-toluene diisocyanate (TDI) and ethylene glycol (EG) as the hard segments. The shape-memory properties and biocompatibility of PLA-PUs were examined. The 50% compressed PLA-PUs could recover almost 100% to their original shape within 10°C from the lowest recovery temperature (22°C–37°C). In the recovery process the PLA-PU showed a maximum contracting stress in the range of 1.5–4 MPa. Cell incubation experiments show that PLA-PU has biocompatibility comparable to that of pure PLA. Therefore, this kind of polyurethane can be used for implanted medical devices with shape memory requirements. |